Target INR for mechanical valves
The 2021 ESC/EACTS Guidelines for the management of valvular heart disease provide target INR for various mechanical valves, emphasizing that a median INR should be targeted instead of an INR range.
Note that a mitral or tricuspid valve replacement qualifies for the higher INR target as a “risk faktor”.
| Prosthesis thrombogenicity | Patient-related risk factors: Mitral or tricuspid valve replacement; previous thromboembolism; atrial fibrillation; mitral stenosis of any degree; LVEF <35%. | |
|---|---|---|
| none | ≥1 risk faktor | |
| Low Carbomedics, Medtronic Hall, ATS, Medtronic Open-Pivot, St Jude Medical, Sorin Bicarbon | 2.5 | 3.0 |
| Medium Other bileaflet valves with insufficient data. | 3.0 | 3.5 |
| High Lillehei-Kaster, Omniscience, Starr-Edwards (ball-cage), Bjork-Shiley and other tilting-disc valves. | 3.5 | 4.0 |
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